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KMID : 0380219800130030143
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Journal of Biochemistry and Molecular Biology
1980 Volume.13 No. 3 p.143 ~ p.150
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The Effect of Ginseng Saponin on Secretion of Bile Acids and Absorption of Lipids in Intestine of The Rat
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Cho, Young Dong/조영동
Kim, Choong Won/Kim, Il/김충원/김일
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Abstract
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In this experiment, it was attempted to observe the effect of saponin, one of the major compounds of Korean Ginseng, on secretion of bile acids and absorption of lipids in the small intestine of the rat, in vivo, and the following results were obtained.
1) Under the experimental condition described, it was observed that the ginseng saponin did not affect the volume of bile juice secreted from the liver but increased 2 to 4.5 times the concentration of cholate contained in the bile juice and the gastrin level in the blood.
2) In the case of cannulation method of obstructing the entrance of bile juice and pancreatic juice into the small intestine, the ginseng saponin stimulated about 2 times the rate of absorption of lipids in the small intestine of the rat.
3) Without cannulation method, the ginseng saponin also stimulated the absorption of lipids in the small intestine of the rat.
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